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Jonathan Brennan-Badal

Jonathan Brennan-Badal

CEO
Opentrons
21 March 2024

Can you provide a general introduction to what Opentrons does for our readers who may not be familiar with your operations?

Opentrons specializes in developing robots designed specifically for scientists, aiming to revolutionize wet labs by automating their processes. This automation allows scientists to conduct more experiments efficiently, thereby accelerating discoveries. Our robots are tailored to support the dynamic and evolving needs of wet labs worldwide, enabling these labs to perform a wider range of experiments at a reduced cost and with greater efficiency.

Could you elaborate on the protocol library, the introduction of generative AI tools, and how these innovations are transforming lab automation?

Our approach to transforming lab automation centers around addressing the significant challenges faced by scientists in wet labs, primarily the lack of access to automation tools. With over four million people working in such environments globally, less than 10% have automation support, leading to manual, time-consuming tasks. We're changing this by making lab automation more accessible and affordable, reducing costs by tenfold and simplifying the use of these tools. This shift not only overcomes financial barriers but also introduces a level of flexibility and adaptability in lab work through our protocol library and generative AI tools. These advancements enable rapid programming of robots to meet the ever-changing needs of research, significantly cutting down the time and effort required to set up and execute experiments.

What impact do you believe these technological advancements will have on the scientific research process?

The impact of our technological advancements on scientific research is profound, particularly in how we address the bottleneck in lab productivity. By enabling scientists to automate routine tasks, we're paving the way for a dramatic increase in the number of experiments conducted and discoveries made.

For instance, in sequencing, the cost of sample preparation now exceeds the use of the sequencers themselves due to manual labor. Automating these processes can significantly reduce costs and increase throughput, shifting the bottleneck away from manual labor and towards more efficient, automated solutions. This paradigm shift mirrors the efficiency seen in industries like Amazon's fulfillment centers, highlighting the potential for robotics to enhance productivity in the life sciences.

How has the market reacted to these innovations in lab automation and efficiency?

The market's response to our innovations has been overwhelmingly positive, as evidenced by the rapid adoption of our OT2 robot and the even faster uptake of our latest product, the Flex Robot. This enthusiasm reflects a strong demand for affordable, user-friendly automation in the life sciences, pushing the boundaries of what our platforms can achieve. Our success indicates a significant shift towards automation among labs that previously viewed such technology as inaccessible, marking a turning point in how automation is perceived and utilized in scientific research.

What are your plans for scaling up to meet the growing demand for your products?

Our strategy for scaling up involves a deep commitment to vertical integration, similar to Tesla's approach to manufacturing. By controlling the design, manufacturing, and assembly of our robots and their components, we've positioned ourselves to respond quickly to surges in demand, such as those experienced during the COVID-19 pandemic. This level of control over our supply chain enabled us to exponentially increase our manufacturing capacity within months, demonstrating our unique ability to scale operations and meet the global demand for lab automation. This approach not only ensures the affordability and usability of our products but also highlights our capacity to overcome challenges and seize opportunities for growth in the rapidly evolving field of lab automation.

Looking towards the future, how do you envision the evolution of lab automation and Opentrons' role in it?

In the medium term, we see vast opportunities for innovation beyond the current applications in wet labs, which involve handling liquids. Our ambition extends to automating the entire lab ecosystem, making it 10x more cost-efficient than current alternatives. This vision includes creating a foundation that not only facilitates the automation and scalability of lab operations through our tools but also offers these capabilities as cloud services. We aim to blur the lines between in-house lab work and outsourced tasks, providing a seamless integration of services on a common platform. This strategy is geared towards accelerating discovery and innovation across the life sciences, fundamentally changing how scientific research is conducted.

Why has the life science industry been slower to adopt automation compared to other sectors?

The life science industry's slow adoption of automation can largely be attributed to the complexity and precision required in wet lab work. Achieving a tenfold reduction in the cost of these activities necessitates a comprehensive overhaul of not just the equipment, like liquid handlers, but also the components that make up these systems. This level of innovation requires a significant amount of effort and a willingness to take a holistic, vertically integrated approach. Few companies are prepared to undertake this challenge, but those that do, like Opentrons, draw inspiration from success stories like Apple and Tesla in other industries. Our unique stance in the life science space is characterized by our commitment to this deep, vertically integrated strategy, positioning us to make a profound impact.

How are you addressing the challenge of raising awareness and adoption of your automation solutions among potential users?

Interestingly, raising awareness and encouraging adoption have not been significant challenges for us. Our consistent year-on-year growth, even before establishing a formal sales organization, was fueled by strong inbound interest. This demand stems from a wide recognition within the industry of the need for affordable, implementable solutions. Our client base, including major pharmaceutical companies and research universities, has expanded organically due to this demand. Our products' ease of use, combined with their affordability compared to competitors, makes them an attractive option for labs seeking automation solutions. This ease of adoption, coupled with our competitive edge in functionality and cost, has facilitated our continued success in the market without the need for extensive sales efforts.